Volume I · Brain Lab · A LifeByLogic Flagship Tool

How old is your brain?

The Brain Age Index estimates your brain's biological age from 17 evidence-based factors — built on the 2024 Lancet Commission on Dementia Prevention and MRI Brain Age Gap research from the UK Biobank (n > 38,000).

Factors Assessed 17 evidence-based
Research Basis Lancet Commission 2024
Time to Complete ~3 minutes
Your Data Never leaves your browser

Answer honestly.

Every input updates your result in real-time. Nothing is submitted or stored — the calculation runs entirely in your browser. Your answers stay between you and your device.

i. You Baseline
Baseline
This is the starting point. Your brain age will be calculated relative to this.
years
Women have a slightly higher lifetime dementia risk; the index adjusts for this.
First-degree relatives with dementia raises risk modestly.
ii. Cardiometabolic Health Midlife window
Normal < 120/80 · Elevated 120-129/<80 · Stage 1 ≥ 130/80 · Stage 2 ≥ 140/90
Optimal < 100 · Near optimal 100-129 · Borderline 130-159 · High ≥ 160 (mg/dL)
Based on your most recent medical assessment.
Normal 18.5-24.9 · Overweight 25-29.9 · Obese ≥ 30
iii. Senses Often overlooked
Uncorrected hearing loss is the single largest modifiable factor in the Lancet 2024 report (PAF 7%).
Untreated vision loss was newly added in Lancet 2024.
iv. Lifestyle Most modifiable
WHO recommends 150+ min/week of moderate activity or 75+ min vigorous.
Heavy in leafy greens, berries, nuts, olive oil, fish; limited red meat, sweets, fried food.
Smoking is one of the strongest modifiable factors in brain age research.
Heavy = > 21 units/week. One unit = 10g pure alcohol (~1 small glass of wine).
v. Sleep 1-3 year brain age effect
Both insufficient and excessive sleep are associated with accelerated brain aging.
Feeling rested, infrequent waking, consistent bedtime and wake times.
vi. Mind & Social The connection factor
Depression is a bidirectional risk factor — both symptom and cause of brain aging.
Meaningful social engagement — not just contact. Late-life isolation PAF is 5%.
Persistent stress over months/years, not acute stress.
vii. Cognitive Reserve Your buffer
Low early-life education has a PAF of 5% — the largest early-life factor.
Reading, problem-solving, creative work — not passive consumption.
Language, instrument, craft, new sport — anything that requires sustained novel learning.
viii. Environment & History Often invisible
Based on your city/area's typical PM2.5 levels.
Including concussions. Each additional injury compounds risk.
Methodology

How the Brain Age Index is calculated.

The LifeByLogic Brain Age Index (LBL-BAI) is a weighted composite score combining 17 evidence-based factors that have been shown in peer-reviewed neuroscience literature to predict the brain age gap — the difference between an individual's chronological age and their estimated biological brain age as derived from MRI or clinical biomarkers.

Its two primary research foundations are:

The 2024 Lancet Commission on Dementia Prevention, which identifies 14 modifiable risk factors accounting for approximately 45% of global dementia cases, with weights derived from meta-analyses of over 1 million participants.
The MRI Brain Age Gap literature, particularly analyses of the UK Biobank (n = 38,967) and ENIGMA consortium cohorts, which demonstrate that MRI-based brain age has a mean absolute error of 2.4-2.5 years and that lifestyle factors account for up to 21% of the variance.

Each factor contributes a weighted adjustment (in years) to the individual's chronological age. The weights reflect published population attributable fractions (PAFs), effect sizes from cohort studies, and MRI-derived brain age gap associations. Sleep and chronic stress — not in the Lancet 2024 factor list — are included because of their well-established association with MRI-measured brain age acceleration.

Factor Weights & Sources

Factor Evidence Source Max Impact
Hearing loss (uncorrected)
Lancet 2024, PAF 7%
+2.5 yrs
LDL cholesterol (elevated)
Lancet 2024 (new), PAF 7%
+2.5 yrs
Low education
Lancet 2024, PAF 5%
±2.0 yrs
Social isolation (late life)
Lancet 2024, PAF 5%
±2.0 yrs
Current smoking
Stoitsas et al. 2025 (Aging Brain)
+3.0 yrs
Physical inactivity
UK Biobank BAG studies
±2.5 yrs
Poor sleep
PMC12730621 (2025), n>25,000
+3.0 yrs
Chronic stress
GeroScience 2025, cohort n=211
±2.5 yrs
Depression
Lancet 2024, PAF 3%
+2.0 yrs
Traumatic brain injury
Lancet 2024, PAF 3%
+2.0 yrs
Air pollution (PM2.5)
Lancet 2024, PAF 3%
+2.0 yrs
Hypertension
Lancet 2024, PAF 2%
+2.0 yrs
Diabetes / pre-diabetes
Lancet 2024, PAF 2%
+2.0 yrs
Obesity
Lancet 2024, PAF 1%
+1.5 yrs
Excessive alcohol
Lancet 2024, PAF 1%
+2.5 yrs
Untreated vision loss
Lancet 2024 (new), PAF 2%
+2.0 yrs
Diet quality (MIND/Med)
FINGER trial; cohort studies
±2.0 yrs

Note: The Brain Age Index is an educational tool designed to surface modifiable areas of lifestyle and health. It is not a medical diagnosis. For clinical assessment of cognitive health, consult a healthcare provider.

Sources & Citations

The research behind the index.

  1. Livingston G, Huntley J, Liu KY, et al. Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission. The Lancet. 2024;404(10452):572-628. doi:10.1016/S0140-6736(24)01296-0
  2. Stoitsas K, Bakx P, Voortman T, Yu J, Roshchupkin G, Bos D. Contributions of lifestyle, education, and cardiovascular risk factors to the brain age gap. Aging Brain. 2025. doi:10.1016/j.nbas.2025.100149
  3. Brain Age Acceleration on MRI Due to Poor Sleep: Associations, Mechanisms, and Clinical Implications. 2025 systematic review across > 25,000 participants. PMC12730621.
  4. Brain age gap as a predictive biomarker that links aging, lifestyle, and neuropsychiatric health. Communications Medicine. 2025. Analysis of UK Biobank (n=38,967), ADNI (n=1,402), and PPMI (n=1,182) cohorts.
  5. Stephan BCM, et al. Population attributable fractions of modifiable risk factors for dementia: a systematic review and meta-analysis. The Lancet Healthy Longevity. 2024;5(6):e406-e421.
  6. A physically and mentally active lifestyle relates to younger brain and cognitive age. GeroScience. 2025. Cohort study n=211 cognitively unimpaired older adults.
  7. Mostert CM, et al. Broadening dementia risk models: building on the 2024 Lancet Commission report for a more inclusive global framework. eBioMedicine. 2025.
  8. The potential for dementia prevention in Brazil: a population attributable fraction calculation for 14 modifiable risk factors. Lancet Regional Health Americas. 2025. ELSI-Brazil cohort (n=9,949).
Frequently Asked

Questions about the index.

What exactly is "brain age"?

Brain age is an estimate of your brain's biological state — how well it has aged compared to your chronological age. In research settings, it's measured via MRI scans analyzed by machine learning models trained on large populations. The brain age gap is the difference between your chronological age and your estimated brain age: a negative gap means your brain looks younger than your years, a positive gap means it's aging faster.

How accurate is this calculator?

This is an educational estimate, not a medical diagnosis. It's calibrated against published population-level research, but individual accuracy varies. MRI-based brain age models in validation cohorts have mean absolute errors of 2.4-2.5 years. Questionnaire-based estimates like this one are less precise but capture the most important modifiable levers identified across over 1 million research participants.

Can I actually reduce my brain age?

Yes — and this is the whole point. The 2024 Lancet Commission estimates that addressing the 14 modifiable factors could prevent or delay 45% of dementia cases globally. The most impactful levers are hearing correction, LDL cholesterol management, physical activity, sleep quality, smoking cessation, and social engagement. Your "Top 3 factors aging your brain" panel is designed to show you exactly where to focus.

Why is hearing loss such a big factor?

Hearing loss has the largest population attributable fraction in the Lancet 2024 report (7%). The current leading hypothesis is that uncorrected hearing loss increases cognitive load, reduces social engagement, and may accelerate brain atrophy in the auditory cortex. The good news: hearing aids mitigate most of this risk.

Is my data stored or sent anywhere?

No. Every calculation runs locally in your browser using JavaScript. Nothing you enter is sent to our servers, stored in a database, or used for tracking. You can verify this by opening your browser's developer network tab while using the tool.

Why include sleep and stress if they're not in the Lancet 2024 list?

The Lancet Commission focuses specifically on dementia risk factors with established causal evidence. Sleep and chronic stress are both strongly linked to MRI-measured brain age acceleration — a closely related but distinct outcome. A 2025 systematic review found that suboptimal sleep independently predicts 1-3 years of brain age acceleration across over 25,000 participants. We include these because the tool measures brain age, not just dementia risk.

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